_{Authors: Kisley Di Giuseppe, Kasoka Kasoka, Yasmin Dunkley}

This study investigated the factors influencing preexposure prophylaxis (PrEP) uptake among Black African heterosexuals in the United Kingdom, while using a 2-phase sequential mixed-methods design. Methods: Surveys from 247 mixed-gender participants were followed by focus groups involving 18 women. Results: Despite the general lack of HIV and PrEP awareness, the study found significant associations between HIV testing, HIV awareness, PrEP awareness, and uptake interest. Stigma was also seen as key barrier: PrEP being connected with HIV positivity, promiscuity, and risky behaviors. Conclusion: This study underlines the need for service providers to develop HIV-prevention interventions that take into account the Black African sociocultural contexts in the United Kingdom.